Herpago - Atospharma.com


Properties and actions:

Herpago has anti-inflammatory, mild analgesic and anti-exudative effects. 
Herpago reduces swelling, relieves pain and improves mobility of the joints. 
Herpago; iridoid glycosides and harpagoside contents are cyclooxygenase (COX) inhibitors mainly COX2 and to lesser extent COX1, reducing synthesis of the prostaglandins that play a major role in the causation of inflammation and pain. Herpago reduces the synthesis of TNF alpha and the release of cartilage metabolism regulating cytokine, interleukin-6, thus inhibits the acute phase reaction and production of pyrogens. 
The cytokines interleukin-1 and leuko-treine B4 are not affected. Unlike NSAIDs, Herpago does not cause gastritis, it has a choleretic effect resulting in increased production of bile, and thereby it increases the yield of bicarbonate in the duodenum and neutralizes excessive acidity.


  • Low back pain and sciatica
  • Inflammatory and degenerative forms of rheumatic pain: osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis
  • Sport injuries and sprains, musculoskeletal pains and tendenitis


  • Unless otherwise prescribed by the physician: 1-2 capsules 3 times/day for 6-12 weeks


  • During first trimester of pregnancy

Side Effects:

  • None reported within the therapeutic dose

Each hard gelatin capsule contains:

  • Harpagophytum procumbens dried extract 400 mg (Standardized to contain minimum > 0.5% total Iridoid calculated as Harpagoside)

Pack size:

12 capsules in 2 blisters

Precautions / Drug interactions:

  • Herpago may affect the action of Warfarin, patients should be monitored regularly for adjustment of Warfarin dose