Safamood Forte

Safamood Forte - Atospharma.com

Anti-Depressant

Properties and actions:

Safamood Forte is an active antide- pressant, because it inhibits synaptic reuptake of serotonin and to a lesser extent norepinephrine, resulting in increased levels in the synaptic gap. 
Safamood Forte suppresses interleukin- 6 (IL6), and thereby promotes the deactivation of the hyperactive hypothalamic- pituitary-adrenal axis (HPA).
Safamood Forte indirectly inhibits the secretion of corticosteroids.
Safamood Forte exerts a mild anxiolytic action through the inhibition of the Gamma Amino Butyric Acid (GABA) reup- take pumps.
Safamood Forte is well tolerated and causes no physical dependence, muscle relaxation or cognitive impairment. There has never been a report of toxicity in humans. 

Indications:

  • Mild and moderate depression
  • Obsessive compulsive disorders (OCD)
  • Psychosomatic disorders

Dosage:

 
Depression and OCD
Psychosomatic Disorders
Dosage
1 - 2 Tablets / Day
1 Tablet / Day

Contraindications:

  • Not to be used during pregnancy and lactation

Side Effects:

  • GIT discomforts and headaches are slight and rare
  • Light sensitivity may occur

Each film coated tablet contains:

  • Hypericum perforatum extract 600 mg (Standardized to contain minimum 0.12% hypericin)

Pack size:

20 tablets in 2 blisters

Precautions / Drug interactions:

  • Plasma levels of cyclosporine, Digoxin and Theophylline may be reduced and oral Contraceptive pills are less effective because their metabolism is accelerated 
  • Concomitant administration with Mono-Amine Oxidase Inhibitors (MAOIs) and Selective Serotonin Reuptake Inhibitors (SSRIs) may increase their side effects